Division of labor during trunk neural crest development

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Division of labor during trunk neural crest development.

Neural crest cells, the migratory precursors of numerous cell types including the vertebrate peripheral nervous system, arise in the dorsal neural tube and follow prescribed routes into the embryonic periphery. While the timing and location of neural crest migratory pathways has been well documented in the trunk, a comprehensive collection of signals that guides neural crest migration along the...

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Trunk Neural Crest Has Skeletogenic Potential

During early vertebrate development, neural crest cells emerge from the dorsal neural tube, migrate into the periphery, and form a wide range of derivatives. There is, however, a significant difference between the cranial and trunk neural crest with respect to the diversity of cell types that each normally produces. Thus, while crest cells from all axial levels form neurons, glia, and melanocyt...

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Mesectodermal capabilities of the trunk neural crest of birds.

Orthotopic transplantation experiments have shown that in birds, under normal conditions, mesectodermal capabilities seem restricted to the cephalic neural crest down to the level of the 5th somite. In the present study the mesectodermal capabilities of trunk and lumbar neural crest were investigated at early stages of development by heterotopic, heterospecific transplantation of the neural pri...

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Skeletogenic Fate of Zebrafish Cranial and Trunk Neural Crest

The neural crest (NC) is a major contributor to the vertebrate craniofacial skeleton, detailed in model organisms through embryological and genetic approaches, most notably in chick and mouse. Despite many similarities between these rather distant species, there are also distinct differences in the contribution of the NC, particularly to the calvariae of the skull. Lack of information about oth...

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Control of pathfinding by the avian trunk neural crest.

We have determined the pathways taken by the trunk neural crest of quail and examined the parameters that control these patterns of dispersion. Using antibodies that recognize migratory neural crest cells (HNK-1), we have found that the crest cells take three primary pathways: (1) between the ectoderm and somites, (2) within the intersomitic space and (3) through the anterior somite along the b...

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ژورنال

عنوان ژورنال: Developmental Biology

سال: 2010

ISSN: 0012-1606

DOI: 10.1016/j.ydbio.2010.04.009